作者：Zhou, C.; Truong V. X.; Qu, Y.; Lithgow, T.; Fu, G. D.; Forsythe, J. S.
关键字：antibacterial hydrogel; epoxy-amine ring opening reaction; quaternary ammonium; thiol-ene click chemistry
论文来源：期刊
具体来源：J. Polym. Sci., Part A:Polym. Chem., 2016, 54(5), 656-667
发表时间：2015年

Antibacterial hydrogels containing quaternary ammonium (QA) groups were prepared via a facile thiol-ene “click” reaction using multifunctional poly(ethylene glycol) (PEG). The multifunctional PEG polymers were prepared by an epoxy-amine ring opening reaction. The chemical and physical properties of the hydrogels could be tuned with different crosslinking structures and crosslinking densities. The antibacterial hydrogel structures prepared from PEG Pendant QA were less well-defined than those from PEG Chain-End QA. Furthermore, functionalization of the PEG-type hydrogels with QA groups produced strong antibacterial abilities against Staphylococcus

aureus, and therefore has the potential to be used as an antiinfective material for biomedical devices.